منابع مشابه
An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes.
(89)Zr-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of (89)Zr-labelled (bio)conjugates with improved stability.
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Citrate was used as chelating or morphology regulating agent in this study. In the presence of regulating agent a two-dimensional monetite phase evolved into three-dimentional hydroxyapatite microspheres with an average diameter of 4 µm. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) studies revealed the importance of Ca/citrate ratio in regulating the particle m...
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The initial evaluation of a novel thiolactone bifunctional chelating agent, /, for facile introduction of the diaminedithiol (DADT) ligand system onto proteins for subsequent labeling with "Te under mild conditions is presented. For human serum albumin and a monoclonal anti-colon carcinoma antibody (B72.3), time-dependent coupling was achieved at pH 7-9 at room temperature. The coupled proteins...
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ژورنال
عنوان ژورنال: Drug Delivery System
سال: 2018
ISSN: 0913-5006,1881-2732
DOI: 10.2745/dds.33.51